Endocrine Abstracts

An 89 years old caucasian female patient with antecedents of hemithyroidectomy in 2016 due to benign nodular disease, and actually suplemented with 0.1 mg/day of levothyroxine, was referred to the Endocrinology consultation because of a primary hyperparathyroidism diagnosed in the sequence of the study of an episode of nephrolitiasis that happened in 2012 and a diagnosis of osteoporosis that was established in 2017. A 99mTc-Sestamibi revealed an augmented right inferior parath...

Virilizing ovarian tumors are a rare cause of hyperandrogenism; they account for 1–2% of all ovarian tumors being the Leydig cell tumor the most common one.We report the case of a 76-year old woman with type 2 diabetes that was referred for androgenic alopecia with 3 years evolution and a recent facial, peri-areolar and dorsal hirsutism. A diagnosis of hypertension was made 18 months previously, and she was on a four anti-hypertensive drug regimen. ...

Introduction: Adrenal incidentaloma are becoming very frequent. Bilateral adrenocortical adenomas are a rare cause of ACTH-independent Cushing syndrome.Clinical case: A 64-year-old hypertensive woman presented with bilateral adrenal incidentaloma detected on the evaluation as a living kidney donor candidate. She was normotensive (129/87 mmHg) on monotherapy, BMI – 24.8 kg/m2, with no recent weight gain, hirsutism, striae or mood disturban...

Aims: The aim of our study was to evaluate the incidence of coronary artery disease (CAD) and heart failure (HF) in diabetic and nondiabetic patients admitted to a central hospital in the North of Portugal between 1989 and 2004.Materials and methods: Data from the Hospital Coding Centre were retrospectively analysed according to International Classification of Diseases (9th version) criteria. We have studied the distribution by age, sex, procedures, caus...

Aims: To evaluate the cardiovascular morbidity in patients with and without hypothyroidism admitted to a central hospital, between 1989 and 2004.Materials and methods: Data from the Hospital Coding Centre were retrospectively analysed according to International Classification of Diseases (9th version) criteria. We have studied the distribution by age, sex, causes and duration of admissions. Statistical analysis was performed with Student’s t-test, &...

Introduction: Lipid profile characterization in women with gestational diabetes mellitus (GDM) and its impact on post-partum dysglycemia remains to elucidate. The aim of this study was to evaluate lipid profile in women with GDM during pregnancy and 8 weeks after and to study its correlation with glycemic control.Methods: This study was carried out in a central hospital in Portugal. All women with GDM diagnosed from January/2014 to December/2015 were enr...

Introduction: Lithium therapy is commonly used in bipolar disorder treatment. Alongside the increasing prevalence of goiter and hypothyroidism, the sustaining use of lithium therapy is associated with several metabolic disorders, such as hypercalcemia and hyperparathyroidism (HPT).Case report: A 64-year-old woman with history of bipolar disorder treated with lithium for several years was referred to our department for evaluation of recurrent hypercalcemi...

Introduction: Thyroid surgery is nowadays associated with low morbidity and extremely low mortality. A consistent association has been observed between high surgical volume and better outcomes. Patients who undergo surgery by a skilled surgeon have fewer complications. On the other hand, different surgical techniques have been associated with different outcomes. Since 1997, thyroid diseases are treated in our department by a multidisciplinary team.Object...

Introduction: ‘PreDiabetes’ was considered as a categories of increased risk for diabetes on the last ADA recommendations in 2010. The proposed diagnostic criteria include an HbA1c value between 5.7 and 6.4%, impaired fasting glucose (IFG) (100–125 mg/dl) and impaired glucose tolerance (IGT) levels (2-h values in the oral glucose tolerance test (OGTT) of 140 to 199 mg/dl). The HbA1c as new diagnostic criteria may actually increase the number of patients diagnose...

The thyroid pathology is an area of special interest in our department. Hyperthyroidism represents 3.4% of the 8144 patients followed.The aim of this study is to characterize the therapeutic approach in patients with Grave’s disease (GD) and toxic nodular disease (TND).Retrospective study of 217 patients diagnosed with GD and TND, evaluated according parameters of therapeutic option, efficacy, relapse rate and associated compl...